A turn-on fluorescent sensor for the discrimination of cystein from homocystein and glutathione.
نویسندگان
چکیده
We report a turn-on fluorescent sensor based on nitrothiophenolate boron dipyrromethene (BODIPY) derivatives for the discrimination of cystein (Cys) from homocystein (Hcy) and glutathione (GSH). The sensor was applied for detection of Cys in living cells.
منابع مشابه
A dual-response BODIPY-based fluorescent probe for the discrimination of glutathione from cystein and homocystein† †Electronic supplementary information (ESI) available: Synthesis, spectroscopic properties, NMR and mass spectra. See DOI: 10.1039/c5sc00216h Click here for additional data file.
1. Time dependent spectral changes of BODIPY-S in the presence of thiols. ......S2 2. MS of BODIPY-S with GSH, Cys and Hcy..............................................S3 3. Photophysical spectra of BODIPY 4 and BODIPY-S +Cys..........................S4 4. Time dependent Spectral changes of S-S-BODIPY in the presence of thiols. ...S5 5. NMR and MS of the product of S-S-BODIPY with thiols..........
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 13 شماره
صفحات -
تاریخ انتشار 2013